Daily Exam Question - March 4, 2014 - Gynecology
Which of the following pharmacological options are approved by the FDA as first-line treatment for a T-score of -2.7?
A. Calcium and Vitamin D
Gynecology Surgery Prolog 7th Edition Question # 48 pg. 67 and #97 pg. 136
Osteoporosis: Tscore less than or equal to -2.5
Low bone mass: -1.0 - -2.5
Osteoporosis is a systemic skeletal disease that involves deterioration of bone micro architecture. The WHO defines osteoporosis base on total bone density of the hip. Osteoporosis increases the risk of fractures even in the absence of trauma. Multiple studies show a beneficial effect of systemic estrogen therapy with or without progesterone on decreasing fracture risk. Use of HT for the prevention of osteoporosis should be individualized and take into account the patient's history and vasomotor symptoms. First line pharmacological options determined by the U. S. Food and Drug Administration to be safe and effective for treatment of osteoporosis include bisphosphonates and SERMs